LGB321

SKU: orb2646033

Description

LGB321 is a potent and selective PIM2 kinase inhibitor that suppresses the proliferation of PIM2-dependent multiple myeloma cells. It effectively inhibits key oncogenic pathways, including mTORC1 signaling and BAD phosphorylation, making it a valuable tool for in vitro and in vivo studies of hematological malignancies.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1210417-75-6
• MW: 457.45
• Formula: C₂₃H₂₂F₃N₅O₂
• SMILES: N(C(=O)C=1N=C(C(F)=CC1)C2=C(F)C=CC=C2F)C=3C(=CC=NC3)N4C[C@H](C)[C@@H](O)[C@H](N)C4
• Target: mTOR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46179018