LGB321 monohydrochloride

SKU: orb3133423

Description

LGB321 monohydrochloride is an effective, selective, and orally active ATP-competitive small molecule inhibitor that targets all three PIM kinases. It inhibits proliferation, the mTOR-C1 signaling pathway, and BAD phosphorylation in various blood cancer-derived cell lines. LGB321 monohydrochloride is suitable for research on hematological malignancies.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 1469925-36-7
• MW: 493.91
• Formula: C₂₃H₂₃ClF₃N₅O₂
• SMILES: N(C(=O)C=1N=C(C(F)=CC1)C2=C(F)C=CC=C2F)C=3C(=CC=NC3)N4C[C@H](C)[C@@H](O)[C@H](N)C4.Cl
• Target: mTOR,Pim

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

mTOR,Pim