LEF1 (N) Antibody, Rabbit Polyclonal

SKU: orb67065

Description

Rabbit polyclonal to LEF1.Lymphoid enhancer-binding factor 1 (LEF1) is a transcription factor belonging to a family of proteinsthat share homology with the high mobility group protein-1. LEF1 can bind to a functionally importantsite in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. LEF1 isinvolved in the Wnt signaling pathway, and it may function in hair cell differentiation and folliclemorphogenesis. Mutations in LEF1 have been found in somatic sebaceous tumors. This gene hasalso been linked to other cancers, including androgen-independent prostate cancer.

Research Area

Epigenetics, Neuroscience, Signaling Pathways, Stem Cells, Wnt

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of mouse LEF1
• Molecular Weight: 44
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-LEF1 antibody,anti-Lymphoid enhancerbinding factor 1 antibody,anti-LEF1 antibody,anti-Lef1 antibody,anti-Lef1 antibody

Quick Database Links

UniProt

P27782