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LB-100

SKU: orb1226017

Description

LB-100 (LB100) is a potent serine/threonine protein phosphatase 2A (PP2A) inhibitor; exhibits inhibitory effect in HCC cell lines Huh-7, HepG2, Hep3B, and SNU-449 with mean IC50 of 10 uM; synergistically enhances the activity of doxorubicin and induces expression of HIF-1α and VEGF; significantly enhances tumor growth inhibition by cisplatin in vivo.Brain Cancer Phase 1 Clinical.

Images & Validation

Key Properties

CAS Number1632032-53-1
MW268.3089
Purity>98% (HPLC)
FormulaC13H20N2O4
SMILESO=C(C1C(O2)CCC2C1C(N3CCN(C)CC3)=O)O
TargetProtein Phosphatase/PTP
SolubilityH2O: ≥ 48 mg/mL; DMSO: < 2.9 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

LB100

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Protocol Information

LB-100 (orb1226017)

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% DMSO +
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%

Available Sizes

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200 mg
500 mg
2 mg
$ 120.00
5 mg
$ 170.00
10 mg
$ 290.00
25 mg
$ 440.00
50 mg
$ 630.00
100 mg
$ 910.00