lavendustin C

SKU: orb1303080

Description

Lavendustin C (NSC 666251) is a selective and potent inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. This tool compound is widely used in biochemical and cellular research to study EGFR signaling pathways in vitro, aiding investigations into oncology and cell proliferation.

Research Area

Cardiovascular Research, Neuroscience, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 125697-93-0
• MW: 275.26
• Purity: 97.77%
• Formula: C₁₄H₁₃NO₅
• SMILES: N(CC1=C(O)C=CC(O)=C1)C2=CC(C(O)=O)=C(O)C=C2
• Target: Src,EGFR,CaMK,Tyrosinase
• Solubility: DMSO:60 mg/mL (217.98 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.27 mM)

Bioactivity

• Target IC50:
  EGFR:0.012 μM (IC50)|CaMK II:0.2 μM (IC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Epidermal growth factor receptor, ErbB-1, EGFR, Inhibitor, HDBA, HER1, lavendustin C, inhibit, kinase, NSC 666251, NSC666251, NSC-666251, Ca2+, Calmodulin-dependent protein kinases, Calmodulin-dependent kinases, calmodulin-dependent, CaMK, Src, pp60, tyrosine, tyrosine kinase

Compound Identifiers

PubChem CID

3896