CERS6 Antibody

SKU: orb1239533

Description

CERS6 Antibody

Research Area

Metabolism Research

Images & Validation

• Tested Applications: ELISA, IF, IHC-P, WB
• Reactivity: Human, Mouse, Rat
• Application Notes:
  LASS6 antibody can be used for detection of LASS6 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

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Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: LASS6 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human LASS6.The immunogen is located within the last 50 amino acids of LASS6.
• Target: CERS6
• Purification: LASS6 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: LASS6 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/mL
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LASS6 Antibody: CERS5, LASS6, Ceramide synthase 6, LAG1 longevity assurance homolog 6, CerS6

Western blot analysis of LASS6 in rat brain tissue lysate with LASS6 antibody at (A) 1 and (B) 2 µg/mL.

Immunohistochemistry of LASS6 in mouse brain tissue with LASS6 antibody at 2.5 µg/mL.

Immunofluorescence of LASS6 in Mouse Brain cells with LASS6 antibody at 5 µg/mL.

Quick Database Links

Gene Symbol

CERS6

UniProt

Q6ZMG9

RefSeq:AAI09285

Seong-Hoon Yun, Eun-Hye Sim, Sang-Heum Han, Tae-Rang Kim, Mi-Ha Ju, Jin-Yeong Han, Jin-Sook Jeong, Sung-Hyun Kim, Alexandra S. Silchenko, Valentin A. Stonik, Joo-In Park In vitro and in vivo anti-leukemic effects of cladoloside C2 are mediated by activation of Fas/ceramide synthase 6/p38 kinase/c-Jun NH2-terminal kinase/caspase-8 Oncotarget, 9, 495 (2018)

PubMed: 29416631

Applications

IF, IHC, WB

Reactivity

Human