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Larotrectinib

Larotrectinib

Catalog Number: orb1301362

DispatchUsually dispatched within 3-5 working days
$ 140.00
Catalog Numberorb1301362
CategorySmall Molecules
DescriptionLarotrectinib
CAS Number1223403-58-4
Purity100%
MW428.44
SMILESO[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F
FormulaC21H22F2N6O2
Biological ActivityLarotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase and is highly selective only for the TRK family of receptors(IC50s = 2-20 nM).
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • LOXO-101 [orb610728]

    ≥99%

    1223403-58-4

    428.44

    5 mg, 100 mg, 25 mg
  • (R)-Larotrectinib [orb1687703]

    98%

    1223404-68-9

    428.44

    C21H22F2N6O2

    25 mg, 100 mg, 50 mg
  • Larotrectinib [orb864271]

    > 98%

    1223403-58-4

    428.44

    C21H22F2N6O2

    5 mg, 25 mg
  • Larotrectinib sulfate [orb1300381]

    99.69%

    1223405-08-0

    526.51

    C21H24F2N6O6S

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 2 mg, 500 mg, 1 ml x 10 mm (in DMSO)
  • Larotrectinib (LOXO-101) Sulfate [orb762673]

    > 98%

    1223405-08-0

    5 mg