(R)-Larotrectinib

SKU: orb1687703

Description

(R)-Larotrectinib is a selective TRK inhibitor with potent activity against TrkA (IC50 = 28.5 nM). This compound is a valuable research tool for investigating TRK-driven cancers, inflammatory processes, and infectious diseases in both in vitro and in vivo experimental models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1223404-68-9
• MW: 428.44
• Formula: C₂₁H₂₂F₂N₆O₂
• SMILES: FC1=C([C@@H]2N(CCC2)C3=NC4=C(NC(=O)N5CC[C@@H](O)C5)C=NN4C=C3)C=C(F)C=C1
• Target: Trk receptor,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

58386288