Laprituximab Antibody

SKU: orb1980397

Description

Laprituximab (J2898A) is a humanized monoclonal antibody targeting EGFR, designed as the antibody component of the ADC laprituximab emtansine. It is utilized in oncology research for investigating anti-EGFR therapies, with applications in both in vitro binding assays and in vivo xenograft models of EGFR-expressing cancers.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1622327-38-1
• MW: 145.2 kDa
• Purity: 99.62% (SEC-HPLC)
• Target: EGFR

Bioactivity

• In Vivo:
  In the H292 xenograft tumor model, the minimum effective dose of Laprituximab was 3 mg/kg.

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

J2898 A, J2898A

Quick Database Links

Gene Symbol

EGFR