L-SelenoMethionine

SKU: orb1689898

Description

L-SelenoMethionine

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3211-76-5
• MW: 196.11
• Purity: 98.55% (May vary between batches)
• Formula: C₅H₁₁NO₂Se
• SMILES: [C@@H](C(O)=O)(CC[Se]C)N
• Target: Apoptosis,Endogenous Metabolite,Amino Acids and Derivatives
• Solubility: DMSO:< 1 mg/mL (insoluble or slightly soluble);H2O:27.5 mg/mL (140.23 mM)

Bioactivity

• In Vitro:
  At 5 μM, L-selenomethionine selectively induces apoptosis in LNCaP prostate cancer cells without affecting non-cancerous cells . c-Myc, cyclin C, proliferating cell nuclear antigen, cyclin-dependent kinase (cdk)1, cdk2, cdk4, cyclin B and cyclin D2 mRNA levels were lower in selenium-deficient cells than in the cells supplemented with 0.25 micromol/L selenomethionine. The phosphorylation state of total cellular protein was higher (57%) in selenium-supplemented cells than in selenium-deficient cells .

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

peroxidase, selenium, inhibit, L-(+)-Selenomethionine, L SelenoMethionine, L-SelenoMethionine, LSelenoMethionine, Inhibitor, Endogenous Metabolite, EndogenousMetabolite, glutathione, dietary, chemopreventive, cancer, Amino Acids and Derivatives, AminoAcidsandDerivatives, Apoptosis

Compound Identifiers

PubChem CID

105024