L-2-Hydroxyglutaric acid

SKU: orb1989679

Description

L-2-Hydroxyglutaric acid (L-2-HG) is a compartmentalized oncometabolite that acts as a substrate for L2HGDH. It functions as an inhibitor of histone demethylases and activates the mTOR-ATF4 signaling pathway. This small molecule is a valuable tool for research in cancer metabolism, epigenetics, and biosensor development in both in vitro and in vivo models.

Research Area

Epigenetics & Chromatin, Metabolism Research

Key Properties

• CAS Number: 13095-48-2
• MW: 148.11
• Formula: C₅H₈O₅
• SMILES: [C@H](CCC(O)=O)(C(O)=O)O
• Target: Mitochondrial Metabolism,Endogenous Metabolite,Histone Demethylase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

439939