Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

KU-60019

SKU: orb1686165

Description

KU-60019 is a potent and selective ATM kinase inhibitor with an IC50 of 6.3 nM. It is widely used in research to investigate DNA damage response pathways, both in cellular studies and in vivo models, to explore oncology and radiobiology.

Research Area

Molecular Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number925701-46-8
MW547.67
FormulaC30H33N3O5S
SMILESC[C@H]1CN(CC(=O)Nc2ccc3Sc4c(Cc3c2)cccc4-c2cc(=O)cc(o2)N2CCOCC2)C[C@@H](C)O1
TargetATM/ATR
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.03 mM);DMSO:90 mg/mL (164.33 mM)

Bioactivity

Target IC50
DNA-PKcs:1.7 μM|ATM:6.3 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

925701-49-1, ATM, ATR, KU 60019, KU60019, KU-60019

Similar Products

  • KU60019 [orb1305429]

    99.00% (May vary between batches)

    925701-49-1

    547.67

    C30H33N3O5S

    5 mg, 10 mg, 1 mg, 50 mg, 1 ml x 10 mM (in DMSO), 25 mg
  • KU-60019 (b) [orb1223633]

    >98% (HPLC)

    925701-49-1

    547.67

    C30H33N3O5S

    5 mg, 10 mg, 25 mg, 100 mg, 200 mg, 500 mg, 1 g
  • KU-60019 [orb1904109]

    925701-49-1, 925701-46-8

    10 mg, 100 mg, 1 ml x 10 mM (in DMSO), 50 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

100 mg
$ 890.00
250 mg
$ 1,600.00
1 g
$ 3,160.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry