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KU-60019 (b)

SKU: orb1223633

Description

KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM in cell-free assays, 270- and 1600-fold more selective for ATM than DNA-PK and ATR,and is a highly effective radiosensitizer.

Images & Validation

Key Properties

CAS Number925701-49-1
MW547.67
Purity>98% (HPLC)
FormulaC30H33N3O5S
SMILESO=C(NC1=CC(CC2=C(C(C3=CC(C=C(N4CCOCC4)O3)=O)=CC=C2)S5)=C5C=C1)CN6C[C@H](C)O[C@H](C)C6
TargetATM/ATR
SolubilityDMSO: 18 mg/mL warmed (32.86 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

KU60019 | KU 60019 | KU-60019.
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Protocol Information

KU-60019 (b) (orb1223633)

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5 mg
$ 120.00
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25 mg
$ 260.00