KSK94

SKU: orb1944240

Description

KSK94 is a potent and selective histamine H3 receptor antagonist (Ki = 7.9 nM) with additional affinity for sigma-2 receptors. This pharmacological profile makes it a useful research tool for investigating mechanisms and potential treatments for neuropathic and inflammatory pain in both in vitro and in vivo models.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2566716-07-0
• MW: 398.5
• Purity: 99.60% (May vary between batches)
• Formula: C₂₅H₂₆N₄O
• SMILES: N#CC=1C=CC(=CC1)C2=CC=C(OCCCN3CCN(C=4C=CN=CC4)CC3)C=C2
• Target: Histamine Receptor,Sigma receptor

Bioactivity

• Target IC50:
  σ1 receptor:2958 nM|H3 receptor:7.9 nM|σ2 receptor:75.2 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

H3 receptor, Histamine Receptor, HistamineReceptor

Compound Identifiers

PubChem CID

162645254