[KO] Integrin alpha V Rabbit mAb

SKU: orb1565483

Description

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

Research Area

Cardiovascular Research

Images & Validation

• Tested Applications: IHC-P, WB
• Dilution Range: WB: 1/500-1/1000 IHC: 1/50-1/100
• Reactivity: Human, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Monoclonal
• Isotype: IgG
• Clone No.: R03-6E3
• Immunogen: Recombinant protein of human Integrin alpha V
• Target: ITGAV
• Molecular Weight: Calculated MW: 116 kDa; Observed MW: 135 kDa
• Purification: Affinity Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% rAlbumin.
• Concentration: 0.3 mg/ml
• Disclaimer: For research use only

Alternative Names

ITGAV; MSK8; VNRA; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51

Western blot analysis of Integrin alpha V in C6, 3T3, Hela lysates using Integrin alpha V antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using Integrin alpha V antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Quick Database Links

Gene Symbol

ITGAV

UniProt

P06756