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KL1333

SKU: orb1307952

Description

KL1333 is an orally bioavailable small molecule that acts as an NQO1 substrate to elevate cellular NAD+ levels. This NAD+ modulation activates the SIRT1/AMPK/PGC-1α axis, enhancing mitochondrial function and energy metabolism, as demonstrated in studies using MELAS patient fibroblasts.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1800405-30-4
MW240.26
Purity99.89%
FormulaC14H12N2O2
SMILESCC(C)c1nc-2c([nH]1)C(=O)C(=O)c1ccccc-21
TargetMitochondrial Metabolism,NADPH,Reductase
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (20.81 mM);DMSO:245 mg/mL (1019.73 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Mitochondrial Metabolism, MitochondrialMetabolism, KL 1333, KL1333, KL-1333, inhibit, NQO1, NQO1 activator 1, Inhibitor

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  • KL1333 [orb1218606]

    >98% (HPLC)

    1800405-30-4

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    C14H12N2O2

    25 mg, 1 g, 500 mg, 200 mg, 5 mg, 50 mg, 100 mg, 2 mg, 10 mg
Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

KL1333 (orb1307952)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 140.00
5 mg
$ 240.00
1 ml x 10 mM (in DMSO)
$ 300.00
10 mg
$ 330.00
25 mg
$ 570.00
50 mg
$ 830.00
100 mg
$ 1,110.00
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