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Catalog Number | orb1309509 |
---|---|
Category | Small Molecules |
Description | Kira8 |
CAS Number | 1630086-20-2 |
Purity | 98.07% |
MW | 601.12 |
SMILES | Cc1ccc2c(NS(=O)(=O)c3ccccc3Cl)cccc2c1Oc1ncccc1-c1ccnc(N[C@H]2CCCNC2)n1 |
Formula | C31H29ClN6O3S |
Biological Activity | Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity (IC50: 5.9 nM). |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |