Kira8 Hydrochloride

SKU: orb1709333

Description

Kira8 Hydrochloride is a potent and selective allosteric inhibitor of IRE1α RNase activity, exhibiting an IC50 of 5.9 nM. This small molecule is a valuable research tool for investigating the unfolded protein response (UPR) in cellular models and has been utilized in preclinical studies targeting endoplasmic reticulum stress-related diseases.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	2250019-92-0
MW	637.58
Formula	C₃₁H₃₀Cl₂N₆O₃S
SMILES	Cl.Cc1ccc2c(NS(=O)(=O)c3ccccc3Cl)cccc2c1Oc1ncccc1-c1ccnc(N[C@H]2CCCNC2)n1
Target	IRE1,Adenosine Receptor

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

134160238 ↗

Key Properties

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No computed properties available.

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