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KI-CDK9d-32

SKU: orb3027996

Description

KI-CDK9d-32 is a CDK9 PROTAC degrader with a DC50 of 0.89 nM. It facilitates the ubiquitination and degradation of CDK9, inhibits the MYC pathway, and disrupts nucleolar homeostasis. KI-CDK9d-32 demonstrates anticancer activity.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3054009-82-1
MW703.83
FormulaC39H45N9O4
SMILESO=C1C=2C(CN1C3C(=O)NC(=O)CC3)=CC(=CC2)N4CCN(CC5=CC=C(C(N[C@H]6C[C@H](NC=7N8C(N=C(CCC)C7)=CC=N8)CC6)=O)C=C5)CC4
Targetc-Myc,PROTACs,CDK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information