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Catalog Number | orb2645891 |
---|---|
Category | Small Molecules |
Description | (KFF)3K is a cell-penetrating peptide that enhances the absorption of other antibiotics by disrupting the outer membrane of bacteria. This compound introduces a hydrocarbon scaffold that induces its antibacterial properties, rendering it an effective antimicrobial peptide. Additionally, (KFF)3K has potential applications in the development of novel antimicrobial agents. |
MW | 1412.76 |
CAS Number | 622402-94-2 |
Formula | C78H105N15O10 |
SMILES | [C@H](CC1=CC=CC=C1)(C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)CCCCN)=O)=O)NC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@H](CC6=CC=CC=C6)NC([C@H](CCCCN)N)=O)=O)=O)CCCCN)=O |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
For example, if the dosage of your experiment is 10mg/kg, the weight of each animal is 50g, and the volume of the dosing is 100μL, then the working solution concentration of your experiment is 5mg/mL. If the formula you used is 5% DMSO+ 30% PEG300+ 5% Tween 80 + 60% Saline/PBS/ddH2O, the preparation method is as follows:
Mother liquor preparation method: 5mg of drug dissolved in 100μL DMSO (mother liquor concentration is 50mg/mL). Preparation method of in vivo formulation: For 1mL of working solution preparation, take 50μL of DMSO mother liquor, add 300 μL of PEG300 to mix well and clarify, then add 50μL of Tween-80 to mix well and clarify, and finally add 600μL of Saline/PBS/ddH2O to mix well and clarify.