Ketorolac

SKU: orb1306372

Description

Ketorolac tromethamine (Acuvail) is a heterocyclic acetic acid NSAID that functions as a potent cyclooxygenase (COX) inhibitor, suppressing prostaglandin synthesis. It is widely used in research for investigating pain, inflammation, and fever models in both in vitro cellular assays and in vivo animal studies.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 74103-06-3
• MW: 255.27
• Purity: 99.40% (May vary between batches)
• Formula: C₁₅H₁₃NO₃
• SMILES: OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1
• Target: Apoptosis,COX
• Solubility: DMSO:45 mg/mL (176.28 mM);H2O:70 mg/mL (274.22 mM)

Bioactivity

• Target IC50:
  COX-2:120 nM |COX-1:20 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclooxygenase, cystoid macular edema, COX, COX-1, COX-2, Apoptosis, anticancer, Acuvail, Acular, allergic conjunctivitis, Macril, ovarian cancer, oral cancer, ophthalmic solution, intraoperative miosis, NSAID, inhibit, Ketorolac, Inhibitor, Sprix, RS 37619, RS37619, RS-37619, postoperative ocularinflammation, Toradol

Compound Identifiers

PubChem CID

3826