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KDM5B (N) Antibody, Rabbit Polyclonal
Catalog Number: orb66907
| Catalog Number | orb66907 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to KDM5B.Lysine (K)-specific demethylase 5B (KDM5B) is a ubiquitously expressed nuclear protein. It is ahistone demethylase that specifically demethylates Lys-4 of histone H3. It can demethylatetrimethylated, dimethylated, and monomethylated Lys-4. It acts as a transcriptional corepressor forFOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressorgenes such as BRAC1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor formelanoma. |
| Clonality | Polyclonal |
| Species/Host | Rabbit |
| Conjugation | Unconjugated |
| Reactivity | Human, Mouse |
| Buffer/Preservatives | 0.01% NaN3 |
| Purity | Affinity purification |
| Immunogen | N-terminal region of human KDM5B |
| UniProt ID | Q9UGL1 |
| MW | 176 |
| Tested applications | WB |
| Dilution range | WB:1:1000-1:5000 |
| Storage | -20°C |
| Alternative names | anti-KDM5B antibody,anti-CT31 antibody,anti-FLJ105 Read more... |
| Note | For research use only |
Western blot analysis of total cell extracts from human Hela(Lane1) and mouse MEF(Lane2) using KDM5B antibody
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