kb NB 142-70

SKU: orb1306594

Description

kb NB 142-70 is a potent and selective inhibitor of all three Protein Kinase D isoforms (PKD1, PKD2, PKD3), exhibiting IC50 values in the low nanomolar range. This small molecule is a valuable research tool for investigating PKD signaling in cellular processes such as proliferation and migration, with applications in both in vitro and in vivo cancer research models.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 1233533-04-4
• MW: 251.32
• Purity: 99.64% (May vary between batches)
• Formula: C₁₁H₉NO₂S₂
• SMILES: Oc1ccc2sc3c(SCCNC3=O)c2c1
• Target: Serine/threonin kinase
• Solubility: DMSO:25.13 mg/mL (99.99 mM)

Bioactivity

• Target IC50:
  PKD1:28.3nM|PKD2:58.7nM|PKD3:53.2 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Protein kinase D, PKD, PKD1, PKD2, PKD3, Serine kinase, threonin kinase, Serinekinase, threoninkinase, inhibit, kb NB 142 70, kb NB 14270, kb NB 142-70, Inhibitor

Compound Identifiers

PubChem CID

45258277