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Catalog Number | orb1950927 |
---|---|
Category | Antibodies |
Description | Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription. |
Species/Host | Rabbit |
Clonality | Recombinant |
Tested applications | ICC, IHC, IP, WB |
Reactivity | Human, Mouse, Rat |
Isotype | Rabbit IgG |
Immunogen | A synthesized peptide derived from human KAT7 / HBO1 / MYST2 |
Antibody Type | Recombinant Antibody |
Dilution range | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:100~1:500 IP 1:50 |
Form/Appearance | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Conjugation | Unconjugated |
UniProt ID | O95251 |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Alternative names | HBO1; HBOa; KAT7; MOZ; MYST 2; MYST protein 2; MYS Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
Western blot analysis of KAT7 / HBO1 / MYST2 expression in (1) MCF7 cell lysate; (2) NIH/3T3 cell lysate; (3) C6 cell lysate.