kaempferide

SKU: orb1303723

Description

Kaempferide (4'-Methylkaempferol) is a flavonoid that suppresses the growth of both native and ERβ-overexpressing colon cancer cells. Its anti-proliferative mechanism operates independently of classical estrogen receptor ligand-binding. This compound is a useful research tool for studying ERβ-mediated, non-genomic pathways in oncology, with applications in both in vitro and in vivo cancer models.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 491-54-3
• MW: 300.26
• Purity: 99.64%
• Formula: C₁₆H₁₂O₆
• SMILES: COc1ccc(cc1)-c1oc2cc(O)cc(O)c2c(=O)c1O
• Target: FOXO,GSK-3,Antibacterial,Akt,PI3K,Estrogen/progestogen Receptor,Apoptosis,Estrogen Receptor/ERR,Autophagy,Wnt/beta-catenin,Influenza Virus
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Acetone:Soluble;DMSO:60 mg/mL (199.83 mM)

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

4'-Methylkaempferol, 4'-O-Methylkaempferol, Autophagy, Bacterial, Inhibitor, EstrogenReceptor, Estrogen Receptor/ERR, Estrogen Receptor, ER, ERR, inhibit, Kaempferol 4'-methyl ether, Kaempferol 4'-O-methyl ether, kaempferide, InfluenzaVirus, Influenza Virus, progestogen Receptor, progestogenReceptor

Compound Identifiers

PubChem CID

5281666