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JP-153

SKU: orb1568337

Description

JP-153 (JP153) is a novel small molecule targets the Src-FAK-Paxillin signaling, inhibits Src-dependent phosphorylation of paxillin (Y118) and downstream activation of Akt (S473) in RECs; potently inhibits VEGF-induced proliferation and migration, inhibits retinal neovascularization in the murine oxygen-induced retinopathy model.

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Key Properties

CAS Number1802937-26-3
MW365.385
Purity>98%
FormulaC21H19NO5
SMILESO1C(C2=CC(OC)=C(OC)C(OC)=C2)C2=CC=C3C(=C2NC1=O)C=CC=C3

Storage & Handling

Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • JP-153 [orb3028685]

    1802937-26-3

    365.379

    C21H19NO5

    10 mg, 50 mg
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Key Properties

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JP-153 (orb1568337)

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10 mg
$ 640.00
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