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Catalog Number | orb1305191 |
---|---|
Category | Small Molecules |
Description | JNK-IN-8 |
CAS Number | 1410880-22-6 |
Purity | 99.24% |
MW | 507.59 |
SMILES | N(C=1N=C(C=CN1)C=2C=CC=NC2)C3=C(C)C=C(NC(=O)C4=CC(NC(C=CCN(C)C)=O)=CC=C4)C=C3 |
Formula | C29H29N7O2 |
Biological Activity | JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRβ in A375 cell line. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1410880-22-6 |
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