JD-5037

SKU: orb1226381

Description

A selective, peripherally restricted cannabinoid-1(CB1) receptor blocker with IC50 of 1.5 nM; shows no effect on CB2 (>10 uM); equieffective with its brain-penetrant parent compound in reducing appetite, body weight, hepatic steatosis, and insulin resistance, even though it does not occupy central CB1R or induce related behaviors.

Key Properties

• CAS Number: 1392116-14-1
• MW: 572.506
• Purity: >98% (HPLC)
• Formula: C₂₇H₂₇Cl₂N₅O₃S
• SMILES: CC(C)[C@@H](C(N)=O)/N=C(N1N=C(C2=CC=C(Cl)C=C2)[C@@H](C3=CC=CC=C3)C1)/NS(=O)(C4=CC=C(Cl)C=C4)=O
• Target: Cannabinoid Receptor
• Solubility: DMSO: 10 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

JD 5037 | JD5037

Quick Database Links

Gene Symbol

Cannabinoid Receptor