Jatrorrhizine

SKU: orb1303544

Description

Jatrorrhizine (neprotin) is a protoberberine alkaloid derived from plants like Enantia chlorantha. It exhibits antimicrobial and antifungal properties and acts as a noncompetitive monoamine oxidase inhibitor (IC50 4 µM for MAO-A, 62 µM for MAO-B). This compound is used in research on neurochemistry and infectious diseases in vitro.

Research Area

Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3621-38-3
• MW: 338.38
• Purity: 97.18% (May vary between batches)
• Formula: C₂₀H₂₀NO₄
• SMILES: O(C)C=1C=C2C=3[N+](=CC=4C(C3)=CC=C(OC)C4OC)CCC2=CC1O
• Target: Antibacterial,5-HT Receptor,Cholinesterase (ChE),MAO
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;DMSO:6.67 mg/mL (19.71 mM)

Bioactivity

• Target IC50:
  MAO-A:4 μm|MAO-B:62μm

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Yatrorizine, quaternary isoquinoline, Serotonin Receptor, 5-hydroxytryptamine Receptor, 5HTReceptor, 5-HT Receptor, 5HT Receptor, AChE, alkaloid, Bacterial, antiplasmodial, antiamoebic, antidepressant, antidepressant-like, antioxidant, antimicrobial, Alzheimer's disease, Cholinesterase (ChE), depressive disorder, E. histolytica, Cytotoxic, inhibit, Jatrorrhizine, neuroprotective, neprotin, Inhibitor, MAO-A, MAO-B, falciparum

Compound Identifiers

PubChem CID

72323