JAK1 Antibody (N-term)

SKU: orb305908

Description

Rabbit polyclonal antibody to JAK1

Research Area

Signal Transduction

Images & Validation

• Tested Applications: WB
• Dilution Range: WB - 1:1000
• Reactivity: Human
• Predicted Reactivity: Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: BTD65021
• Immunogen: This JAK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 172-204 amino acids from the N-terminal region of human JAK1.
• Target: JAK1
• Molecular Weight: 133277
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti Tyrosine-protein kinase JAK1 antibody, anti Janus kinase 1 antibody, anti JAK-1 antibody, anti JAK1 antibody, anti JAK1A antibody, anti JAK1B antibody

Western blot analysis of lysates from HT-29, Hela, Jurkat cell line (from left to right), using JAK1 Antibody (N-term). Diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

Quick Database Links

Gene Symbol

JAK1

UniProt

P23458

Yang, Li et al. Enhancing NK cell-mediated cytotoxicity to cisplatin-resistant lung cancer cells via MEK/Erk signaling inhibition Sci Rep, 7, 7958 (2017)

PubMed: 28801607

Xu, Lijun et al. Adipocytes affect castration-resistant prostate cancer cells to develop the resistance to cytotoxic action of NK cells with alterations of PD-L1/NKG2D ligand levels in tumor cells Prostate, 78, 353-364 (2018)

PubMed: 29330929