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JAB-3068

SKU: orb2900937

Description

JAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor, extracted from patent WO2017211303A1, compound 7, has an IC50 of 25.8 nM.

Images & Validation

Key Properties

CAS Number2169223-48-5
MW476.54
Purity>98% (HPLC)
FormulaC22H26F2N6O2S
SMILESS(C1=C2C(N(C(C)=O)CC2(F)F)=CC=C1)C=3C(N)=NC(=CN3)N4CCC5(CC4)[C@H](N)COC5
TargetPhosphatase

Bioactivity

In Vitro
JAB-3068 (SHP2-IN-6) inhibits the proliferation of KYSE-520 cells with an IC50 of 2.17 μM.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • JAB-3068 [orb1691167]

    99.78% (May vary between batches)

    2169223-48-5

    476.54

    C22H26F2N6O2S

    5 mg, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg
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Protocol Information

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500 mg
2 mg
$ 140.00
5 mg
$ 200.00
10 mg
$ 290.00
25 mg
$ 530.00
50 mg
$ 780.00
100 mg
$ 1,060.00