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ITK degrader 2

SKU: orb1982299

Description

ITK Degrader 2 (Compound 30) is a heterobifunctional molecule that induces targeted ubiquitination and degradation of the ITK kinase. This tool compound enables the study of ITK function and its therapeutic potential in immunological and oncological research contexts, both in vitro and in vivo [1].

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2858738-65-3
MW753.88
FormulaC41H49F2N9O3
SMILESC[C@@]12[C@@](C1(F)F)(CC3=C(C2)NN=C3C=4NC=5C(C4)=CC=C(N(C([C@H](C)N6CCN(CC7CCN(CC7)C8=CC=C(C=N8)C9C(=O)NC(=O)CC9)CC6)=O)C)C5)[H]
TargetTyrosine Kinases,Others,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

ITK degrader 2 (orb1982299)

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