ITGA4 (C) Antibody, Rabbit Polyclonal

• Catalog Number: orb67043
• Category: Antibodies
• Description: Rabbit polyclonal to ITGA4.Integrin alpha-4 (ITGA4) is a single-pass type I membrane protein that belongs to the intergrin alphachain family. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. Theyrecognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin.They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S inVCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T inMADCAM1. On activated endothelial cells, integrin VLA-4 triggers homotypic aggregation for mostVLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with targetcells.
• Clonality: Polyclonal
• Species/Host: Rabbit
• Conjugation: Unconjugated
• Reactivity: Human
• Buffer/Preservatives: 0.01% NaN3
• Purity: Affinity purification
• Immunogen: N-terminal region of human ITGA4
• UniProt ID: P13612
• MW: 115
• Tested applications: WB
• Dilution range: WB:1:500-1:1000
• Storage: -20°C
• Alternative names: anti-ITGA4 antibody,anti-Integrin alpha4 antibody,
• Note: For research use only

Western blot analysis of total cell extracts from human Jurkat using ITGA4 antibody