ISR activator 3

SKU: orb3174710

Description

ISR activator 3 (Compound cc81) is the active metabolite of A8. It activates the integrated stress response (ISR) by binding to RIG-I (KD≈ 0.55 μM) without inducing lipid droplet clearance. Additionally, ISR activator 3 enhances the interferon response under viral mimic signaling. This compound is applicable in studies of neurodegenerative diseases and immune stress.

Research Area

Cell Biology

Key Properties

• CAS Number: 332950-12-6
• MW: 451.56
• Formula: C₂₃H₂₁N₃O₃S₂
• SMILES: O=C(OCC)C1=C(SC=C1C=2C=CC=CC2)NC(=O)C=3SC4=NC(=CC(=C4C3N)C)C
• Target: PERK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PERK