Isolongifolene

SKU: orb1709393

Description

(-)-Isolongifolene is a tricyclic sesquiterpene with demonstrated antioxidant, anti-inflammatory, and neuroprotective activities. Research indicates it protects against rotenone-induced toxicity in vitro and in vivo by modulating PI3K/AKT/GSK-3β signaling, supporting its study in neurodegeneration and oxidative stress models.

Research Area

Cell Biology

Key Properties

• CAS Number: 1135-66-6
• MW: 204.35
• Purity: 99.46% (May vary between batches)
• Formula: C₁₅H₂₄
• SMILES: [H][C@]12CC[C@]3(C1)C(=CCCC3(C)C)C2(C)C
• Target: Apoptosis
• Solubility: DMSO:25 mg/mL (122.34 mM);10% DMSO+90% Corn Oil:1 mg/mL (4.89 mM)

Bioactivity

• In Vitro:
  isolongifolene (ILF), a tricyclic sesquiterpene of Murraya koenigii, against rotenone-induced mitochondrial dysfunction, oxidative stress and apoptosis in a cellular model.

Storage & Handling

• Storage: store under nitrogen,store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(-)-Isolongifolene, anticancer, antioxidant, anti-inflammatory, Apoptosis, cytotoxicity, dysfunction, Isolongifolene, inhibit, mitochondrial, Inhibitor, ROS, Rotenone, sesquiterpene, Tricyclic

Compound Identifiers

PubChem CID

11127402