IRBM-Z-1

SKU: orb3211122

Description

IRBM-Z-1 is a non-competitive inhibitor of Zika virus (ZIKV) NS2B-NS3 protease with an IC50 of 1.8 μM. It also inhibits the mutated Dengue virus type 2 (DENV2) and West Nile virus (WNV) NS2B-NS3 proteases, exhibiting IC50 values of 3.9 μM and 4.7 μM, respectively. IRBM-Z-1 effectively inhibits Zika virus replication and reduces virus-induced cytopathic effects, making it useful for research related to ZIKV infection.

Key Properties

• CAS Number: 67629-86-1
• MW: 390.36
• Formula: C₁₉H₁₇F₃N₄O₂
• SMILES: O=C([N-]C=1ON=[N+](C1)C(C)CC=2C=CC=CC2)NC3=CC=CC(=C3)C(F)(F)F
• Target: Anti-infection,Virus Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Anti-infection,Virus Protease