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Catalog Number | orb699595 |
---|---|
Category | Antibodies |
Description | Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. |
Species/Host | Rat |
Clonality | Monoclonal |
Clone Number | AvB6 53a.2 |
Tested applications | FACS, IF, IP, WB |
Reactivity | Human |
Isotype | Rat IgG2a, kappa |
Immunogen | Mouse fibroblasts retrovirally infected with cDNA to express a mouse/human avb6 chimera was used as the immunogen for the Integrin alpha V + beta 6 antibody. |
Dilution range | Immunoprecipitation: 1-2ug/500ug protein,Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 1-2ug/ml,Western blot: 0.5-1ug/ml |
Purity | Protein G affinity chromatography |
Conjugation | Unconjugated |
Formula | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Hazard Information | This Integrin alpha V + beta 6 antibody is available for research use only. |
UniProt ID | P18564, P06756 |
Storage | Store the Integrin alpha V + beta 6 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide). |
Buffer/Preservatives | 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide |
Note | For research use only |
Application notes | Optimal dilution of the Integrin alpha V + beta 6 antibody should be determined by the researcher. |
Expiration Date | 12 months from date of receipt. |
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