Integrin alpha V + beta 6 Antibody

SKU: orb699595

Description

Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Research Area

Epigenetics, Infectious Diseases

Images & Validation

• Tested Applications: FACS, IF, IP, WB
• Dilution Range: Immunoprecipitation: 1-2ug/500ug protein,Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 1-2ug/ml,Western blot: 0.5-1ug/ml
• Reactivity: Human
• Application Notes:
  Optimal dilution of the Integrin alpha V + beta 6 antibody should be determined by the researcher.

Key Properties

• Antibody Type: Primary Antibody
• Host: Rat
• Clonality: Monoclonal
• Isotype: Rat IgG2a, kappa
• Clone No.: AvB6 53a.2
• Immunogen: Mouse fibroblasts retrovirally infected with cDNA to express a mouse/human avb6 chimera was used as the immunogen for the Integrin alpha V + beta 6 antibody.
• Purification: Protein G affinity chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

SDS-PAGE analysis of purified, BSA-free Integrin alpha V + beta 6 antibody (clone AvB6 53a.2) as confirmation of integrity and purity.

Quick Database Links

UniProt

P18564, P06756