Inbrx-105 Antibody

• Catalog Number: orb2949987
• Category: Antibodies
• Description: INBRX-105 is a recombinant humanized bispecific antibody that targets programmed death-ligand 1 (PD-L1) and 4-1BB (CD137), exhibiting potential checkpoint inhibition, immune stimulation, and anti-tumor activity. By binding to 4-1BB on activated T-lymphocytes and PD-L1 on tumor cells, INBRX-105 enhances T-cell co-stimulation and inhibits PD-L1-mediated T-cell suppression, potentially reducing tumor growth. It demonstrates anti-tumor efficacy and increased T-cell frequency in patients with solid tumors and in vivo. Molecular weight: 101.9 kD.
• Target: PD-1/PD-L1
• Clonality: Recombinant
• Conjugation: Unconjugated
• Antibody Type: Inhibitor Antibody
• CAS Number: 2539845-73-1
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Research Area: Cell Biology, Immunology & Inflammation
• Note: For research use only