Ilaprazole sodium

SKU: orb1307528

Description

Ilaprazole sodium (IY-81149 sodium) is an irreversible proton pump inhibitor prodrug. It is activated in acidic parietal cell compartments to form a sulfenamide that covalently inhibits H+/K+ ATPase, suppressing gastric acid secretion. This compound is utilized in research on gastric ulcer models, acid-related disorders, and the pharmacodynamics of PPI mechanisms in both in vitro and in vivo experimental settings.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 172152-50-0
• MW: 388.42
• Purity: 99.06% (May vary between batches)
• Formula: C₁₉H₁₇N₄NaO₂S
• SMILES: O=S(CC1=NC=CC(OC)=C1C)C2=NC3=C([N-]2)C=C(N4C=CC=C4)C=C3.[Na+]
• Target: TOPK|||Proton pump
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.15 mM);DMSO:71 mg/mL (182.79 mM);H2O:50 mg/mL (128.73 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cancer, acid, IY81149, IY-81149, IY-81149 sodium, IY 81149, Ilaprazole, Ilaprazole sodium, inhibit, oral, Inhibitor, gastric, pump, Proton pump, Protonpump, Proton Pump, TOPK, ulcers

Compound Identifiers

PubChem CID

121595900