IL2RB (C) Antibody, Rabbit Polyclonal

SKU: orb67097

Description

Rabbit polyclonal to IL2RB.Interleukin-2 receptor subunit beta (IL2RB) is a type I membrane protein which belongs to the type Icytokine receptor family.The interleukin 2 receptor, which is involved in T cell-mediated immuneresponses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is amonomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity formconsists of an alpha/beta subunit heterodimer, while the high affinity form consists of analpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptorare involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.

Images & Validation

• Tested Applications: WB
• Dilution range: WB:1:1000-1:5000
• Reactivity: Human, Mouse

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: C-terminal region of mouse IL2RB
• Molecular Weight: 61
• Purity: Affinity purification

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Disclaimer: For research use only

Alternative Names

anti-Interleukin 2RB antibody,anti-Interleukin2 receptor subunit beta antibody,anti-IL2 receptor subunit beta antibody,anti-IL2R subunit beta antibody,anti-IL2RB antibody,anti-High affinity IL2 receptor subunit beta antibody,anti-p7075 antibody,anti-CD122 antibody

Western blot analysis of total cell extracts from mouse brain(Lane1),mouse thymus(Lane2) and human HepG2(Lane3) using IL2RB antibody

Quick Database Links

UniProt

P16297