IL1 beta Antibody / IL1B

• Catalog Number: orb2635114
• Category: Antibodies
• Description: This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: IL1B/465
• Tested applications: ELISA
• Reactivity: Human
• Isotype: Mouse IgG2b, kappa
• Immunogen: Recombinant full-length human IL1B protein was used as the immunogen for the IL1B antibody.
• Antibody Type: Primary Antibody
• Dilution range: ELISA (order BSA-free format for coating)
• Conjugation: Unconjugated
• Formula: 1 mg/ml in 1X PBS; BSA free, sodium azide free
• Hazard Information: This IL1B antibody is available for research use only.
• UniProt ID: P01584
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Note: For research use only
• Application notes: Optimal dilution of the IL1B antibody should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.