IL Receptor Antibody

SKU: orb3169744

Description

APX-007 is a human monoclonal antibody expressed in CHO cells that specifically targets IL-6 Receptor alpha (IL-6Rα/CD126). It features a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight of approximately 150 kDa. By binding to IL-6Rα, APX-007 blocks the interaction between IL-6 and its receptor, thereby inhibiting both classical and trans-signaling pathways mediated by IL-6 and suppressing downstream inflammatory cascades. This antibody is a valuable tool for research into autoimmune diseases and chronic inflammation. The recommended isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Clonality	Monoclonal
Target	IL Receptor
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

IL Receptor

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