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Catalog Number | orb66667 |
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Category | Antibodies |
Description | Mouse monoclonal to IL17A.IL-17A is a proinflammatory cytokine produced by activated T cells. IL-17A is found both in glycosylated and nonglycosylated forms. IL-17A regulates the activities of NF-kappaB and mitogen-activated protein kinases, and it can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
Species/Host | Mouse |
Clonality | Monoclonal |
Tested applications | ELISA, WB |
Reactivity | Human |
Immunogen | N-terminal region of human IL-17A |
Dilution range | WB:1:1000-1:5000 |
Purity | Caprylic Acid-Ammonium Sulfate precipitation |
Conjugation | Unconjugated |
MW | 17.5 |
UniProt ID | Q16552 |
Storage | -20°C |
Buffer/Preservatives | 0.02% Thimerosal |
Alternative names | anti-Interleukin 17A antibody,anti-Cytotoxic Tlymp Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human IL-17A protein(100ng) using IL17A antibody