IL-17A (N) Antibody, Mouse Monoclonal

SKU: orb66667

Description

Mouse monoclonal to IL17A.IL-17A is a proinflammatory cytokine produced by activated T cells. IL-17A is found both in glycosylated and nonglycosylated forms. IL-17A regulates the activities of NF-kappaB and mitogen-activated protein kinases, and it can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Research Area

Epigenetics

Images & Validation

• Tested Applications: ELISA, WB
• Dilution range: WB:1:1000-1:5000
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Immunogen: N-terminal region of human IL-17A
• Molecular Weight: 17.5
• Purity: Caprylic Acid-Ammonium Sulfate precipitation
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.02% Thimerosal
• Disclaimer: For research use only

Alternative Names

anti-Interleukin 17A antibody,anti-Cytotoxic Tlymphocyteassociated antigen 8 antibody,anti-CTLA8 antibody,anti-IL17 antibody

Western blot analysis of total cell extracts from human IL-17A protein(100ng) using IL17A antibody

Quick Database Links

UniProt

Q16552