IL-15 mutant Recombinant Protein

• Catalog Number: orb1229914
• Category: Proteins
• Description: IL-15 mutant Recombinant Protein
• Tag: Fc Tag
• Form/Appearance: Lyophilized
• Purity: > 98% (SDS-PAGE). Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
• Target: IL15
• UniProt ID: Q9JKF4
• Protein Sequence: The extracellular domain of human IL-15 (aa 49-162) including mutations at Q149D and Q156D is fused to the N-terminus of the Fc region of human IgG1.
• Source: CHO cells
• Biological Activity: This mutant IL-15/Fc fusion protein specifically binds to the IL-15R, competitively inhibits IL-15-triggered cell proliferation, promotes transplant tolerance, does not activate the STAT-signaling pathway, and exerts a prolonged circulating half-life caused by the modified Fc domain.
• NCBI: NP_751914
• Storage: Stable for at least 1 year after receipt when stored at -20˚°C. Working aliquots are stable for up to 3 months when stored at -20˚°C.
• Buffer/Preservatives: Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 μl sterile water. Add 1X PBS to the desired protein concentration.
• Alternative names: Interleukin-15
• Note: For research use only
• Application notes: This recombinant proteins is for research use only.
• Expiration Date: 6 months from date of receipt.