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IL-15 mutant Recombinant Protein (biotin)
Catalog Number: orb1229913
| Catalog Number | orb1229913 |
|---|---|
| Category | Proteins |
| Description | IL-15 mutant Recombinant Protein (biotin) |
| Tag | Fc Tag |
| Form/Appearance | Lyophilized |
| Purity | > 98% (SDS-PAGE). Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza). |
| Target | IL15 |
| UniProt ID | O88516 |
| Protein Sequence | The extracellular domain of human IL-15 (aa 49-162) including mutations at Q149D and Q156D is fused to the N-terminus of the Fc region of mouse IgG2a. |
| Source | CHO cells |
| Biological Activity | This mutant IL-15/Fc fusion protein specifically binds to the IL-15R, competitively inhibits IL-15-triggered cell proliferation, promotes transplant tolerance, does not activate the STAT-signaling pathway, and exerts a prolonged circulating half-life caused by the modified Fc domain. |
| NCBI | NP_751914 |
| Storage | Stable for at least 6 months after receipt when stored at +4˚°C. |
| Buffer/Preservatives | In PBS and 0.09% sodium azide. |
| Alternative names | Interleukin-15 Read more... |
| Note | For research use only |
| Application notes | This recombinant proteins is for research use only. |
| Expiration Date | 6 months from date of receipt. |
