IKZF3 (vPairTM) Antibodies

SKU: orb131759

Description

Rabbit polyclonal to IKZF3. IKZF3 antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Biorbyt to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody pairs-based assays. The use of a pair of fully characterized vPair antibodies in the same assay can validate signal specificity since vPair antibodies recognize two independent epitopes of the same protein. Different sets of vPair antibodies are developed at Biorbyt to work with specific applications, including antibody pairs arrays, Western blot, IP-Western, ChIP, IHC, and FACS. Zinc finger protein Aiolos (IKZF3) belongs to the Ikaros C2H2-type zinc-finger protein family. IKZF3 is a transcription factor that plays an important role in the regulation of lymphocyte differentiation. IKZF3 plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Additionally, IKZF3 is involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.

Research Area

Epigenetics

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:3000
• Reactivity: Human
• Application Notes:
  WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; ; Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing either the N-terminal or the C-terminal region of human IKZF3.

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal or the C-terminal region of human IKZF3
• Molecular Weight: 58
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Concentration: 100 μg/ml BSA
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti Zinc finger protein Aiolos antibody pairs, anti Ikaros family zinc finger protein 3 antibody pairs, anti ZNFN1A3 antibody pairs

Quick Database Links

UniProt

Q9UKT9