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Catalog Number | orb1730957 |
---|---|
Category | Antibodies |
Description | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
Species/Host | Rabbit |
Clonality | Monoclonal |
Tested applications | IP, WB |
Reactivity | Human |
Isotype | Rabbit IgG |
Immunogen | Recombinant protein of human IGF1 Receptor |
Concentration | 1mg/ml |
Dilution range | IP: 1/20; WB: 1/500-1/1000 |
Conjugation | Unconjugated |
MW | Calculated MW: 155 kDa; Observed MW: 95 kDa |
Entrez | 3480 |
UniProt ID | P08069 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin |
Alternative names | IGF1R; Insulin-like growth factor 1 receptor; Insu Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
IF, IH, IP, WB | |
Human, Mouse, Rat, Zebrafish | |
Rabbit | |
Polyclonal | |
Unconjugated |
ELISA, IHC, WB | |
Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
IH, WB | |
Human, Mouse, Rat, Zebrafish | |
Rabbit | |
Polyclonal | |
Unconjugated |
ICC, IF, IHC, WB | |
Hamster | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
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