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IDH1 Inhibitor 2

SKU: orb1709446

Description

Compound 13 (IDH1 Inhibitor 2) is a potent, covalent inhibitor of IDH1 that targets His315, exhibiting an IC50 of 110 nM. This small molecule is a valuable research tool for studying IDH1-mutant cancers in both cellular and animal models, aiding investigations into oncometabolism and potential therapeutic strategies.

Research Area

Metabolism Research, Metabolism Research; Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2244895-42-7
MW406.48
FormulaC26H22N4O
SMILESC[C@H]1[C@]2([C@@](C=3C(CC2)=CN=C(NC4=CC=CC=C4)N3)(C=C(C#N)C1=O)C5=CC=CC=C5)[H]
TargetDehydrogenase,Isocitrate Dehydrogenase (IDH)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information