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ICAM1 Antibody / CD54

Catalog Number: orb1824744

DispatchUsually dispatched within 5-10 working days
$ 410.00
Catalog Numberorb1824744
CategoryAntibodies
DescriptionRecognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.
ClonalityMonoclonal
Species/HostMouse
IsotypeMouse IgG2b, kappa
ConjugationUnconjugated
ReactivityHuman
ImmunogenA recombinant fragment of the human protein was used as the immunogen for the ICAM-1 antibody.
UniProt IDP05362
Tested applicationsIHC-P
Dilution rangeImmunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Antibody TypePrimary Antibody
Clone NumberICAM1/6606
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Hazard InformationThis ICAM-1 antibody is available for research use only.
NoteFor research use only
ICAM1 Antibody / CD54

IHC staining of FFPE human tonsil tissue with ICAM-1 antibody (clone ICAM1/6606). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

ICAM1 Antibody / CD54

SDS-PAGE analysis of purified, BSA-free CD54 / ICAM-1 antibody (clone ICAM1/6606) as confirmation of integrity and purity.

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    FACS,  IF,  IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg, 100 μg
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    FA,  FACS,  IHC-P

    Human

    Mouse

    Monoclonal

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    20 μg, 100 μg
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    IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg, 100 μg
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    IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg
  • ICAM1 Antibody / CD54 [orb1824746]

    IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg