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Hypophyllanthin

SKU: orb1218144

Description

Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.

Images & Validation

Key Properties

CAS Number33676-00-5
MW430.5
Purity>98% (HPLC)
FormulaC24H30O7
SMILESCOC[C@H](Cc1c2)[C@H](COC)[C@@H](c(cc3)cc(OC)c3OC)c1c1OCOc1c2OC
TargetCalcium Channel
SolubilityDMSO:100 mg/mL (232.29 mM; Need ultrasonic)

Bioactivity

In Vitro
Hypophyllanthin down-regulates COX-2, TNF-α, and IL-1β gene expressions in U937 macrophages by interfering with the activation of NF-κB, MAPKs, and Akt.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

Hypophyllanthin (orb1218144)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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100 mg
200 mg
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5 mg
$ 360.00
10 mg
$ 530.00
25 mg
$ 840.00